Biological Information

Family:

GPCR

Sub Family:

Lysophospholipid (LPA)

Class:

Class A

Protein Name:

LPA1

Uniprot Number:

Q92633

Protein Aliases:

LPA-1|EDG2|Lysophosphatidic acid receptor Edg-2

Gene Name:

LPAR1

Gene ID:

1902

Gene Aliases:

edg-2|rec.1.3|vzg-1|Gpcr26|Mrec1.3|LPA1|GPR26

Accession Number:

NM_057159

Organism:

Human

Construct Details:

Recombinant

Cell Type:

Chem-1

Assay Information

Assay Type:

Functional

Assay Sub Type:

Cell Based

Functional Mode:

Antagonist

Detection Method:

Fluorimetry

Measured Response:

Fluorescence

Testing Information

Incubation:

RT

Control Inhibitor:

Ki 16425

Control Activator:

Oleoyl-LPA (2000 nM)

Test Concentration / Dose:

Eurofins will provide IC/EC50 calculation if 5 or more concentrations are selected.

Test Sample Requirements:

Minimum for 1) Screen: 70 µL of 10 mM stock -OR- 1 mg (pre-weighed) for 10µM finµL testing. 2) Dose Response: 90 µL of 10 mM stock -OR- 1 mg (pre-weighed) for a top concentration at 10 µM.

Minimum Order Quantity:

16

Turnaround Time

Standard:

15 Business Days

Reference Compound Data

PubChem ID

10367662

Name

Ki 16425

Measurement

57.3nM - IC50

Additional Information

Brand:

LeadHunter

Testing Location:

France - Celle L'Evescault

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