Biological Information

Family:

GPCR

Sub Family:

Lysophospholipid (LPA)

Class:

Class A

Protein Name:

LPA1

Uniprot Number:

Q92633

Protein Aliases:

LPA-1|EDG2|Lysophosphatidic acid receptor Edg-2

Gene Name:

LPAR1

Gene ID:

1902

Gene Aliases:

edg-2|rec.1.3|vzg-1|Gpcr26|Mrec1.3|LPA1|GPR26

Accession Number:

NM_057159

Organism:

Human

Construct Details:

Recombinant

Assay Information

Assay Type:

Biochemical

Assay Sub Type:

Binding

Detection Method:

Radiometric

Measured Response:

Scintillation

Testing Information

Ligand:

[3H]LPA

Ligand Kd (nM):

19

Ligand Concentration:

2 nM

Non Specific:

10 µM LPA

Incubation:

90 min at RT

Control Inhibitor:

LPA

Test Concentration / Dose:

Eurofins will provide IC/EC50 calculation if 5 or more concentrations are selected.

Test Sample Requirements:

Minimum for 1) Screen: 60 μl of 10 mM stock -OR- 1 mg (pre-weighed) for 10µM final testing. 2) Dose Response: 90 μl of 10 mM stock -OR- 1 mg (pre-weighed) for a top concentration at 10 µM.

Minimum Order Quantity:

2

Turnaround Time

Standard:

15 Business Days

Reference Compound Data

PubChem ID

4077460

Name

SEW2871

Measurement

nM - IC50

PubChem ID

5283560

Name

Sphingosine 1-phosphate

Measurement

nM - IC50

PubChem ID

Name

LPA

Measurement

15nM - IC50

PubChem ID

Name

phosphatidic acid

Measurement

2700nM - IC50

Additional Information

Brand:

LeadHunter

Testing Location:

France - Celle L'Evescault

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