OVERVIEW
DOCUMENTS/REFERENCES
Biological Information
Background Information:
Evaluation of two compounds in any BioMAP system, individually and in combination. The KF3CT system is comprised of keratinocytes and dermal fibroblasts. It models Th1 type cutaneous inflammation and is an environment that promotes monocyte and T cell adhesion and recruitment. The KF3CT system is relevant for cutaneous responses to tissue damage caused by mechanical, chemical, or infectious agents as well as certain states of psoriasis and dermatitis.
Organism:
Human
Assay Information
Assay Type:
Functional
Assay Sub Type:
Cell Based
Testing Information
Test Concentration / Dose:
Two test agents profiled alone at four concentrations, and in combination in a four-by-four matrix, in triplicate.
Test Sample Requirements:
For Small Molecules: 350uL of a 1000X stock based on the top concentration being tested & standard 3-fold dilutions per system and per Combo. For Biologics: 3.5mL of a 100X stock in PBS or water, based on the top concentration being tested & standard 3-fold dilutions per system and per Combo
Turnaround Time
Standard:
40 Business Days
Clinical Relevance
Therapeutic Area:
Dermatology
Additional Information
Brand:
BioMAP
Testing Location:
USA - St Charles, MO
RELATED SOLUTIONS
BioMAP Diversity PLUS
Item: 89-0001-0903
BioMAP Systems ELECT Menu 1 (KF3CT)
Item: 89-0003-0010
BioMAP Combo ELECT Menu 1 (HDF3CGF)
Item: 89-0015-0009
BioMAP Combo ELECT Menu 1 (KFNo)
Item: 89-0015-0016
BioMAP RNA ELECT (KF3CT)
Item: 89-0035-0010
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