Motilin Human Motilin GPCR Cell Based Agonist & Antagonist Calcium Flux LeadHunter Assay - FR

Background Information:

Motilin receptors belong to the superfamily of G protein-coupled seven transmembrane proteins. G-protein-coupled receptors constitute one of the major signal transduction systems in eukaryotic cells. Coding sequences for these receptors, in those regions believed to contribute to the agonist-antagonist binding site, are strongly conserved across mammalian species. Muscarinic receptors are primarily distributed in the gastrointestinal tract and may also be present in the central nervous sytem.

No. of Assays on Panel:

2

Family:

GPCR

Sub Family:

Motilin

Class:

Class A

Protein Name:

Motilin

Uniprot Number:

O43193

Gene Name:

MLNR

Gene ID:

2862

Gene Aliases:

GPR38|MTLR|MTLR1

Organism:

Human

Cell Type:

CHO-K1