OVERVIEW
DOCUMENTS/REFERENCES
Biological Information
Background Information:
The SafetyScreenPLUS Panel expands upon the SafetyScreen87 Panel by incorporating additional 40 safety targets recommended by the IQ DruSafe Consortium (Brennan RJ, et al., Nat Rev Drug Discov, 2024) and recent publications (Maciag M and Karamyan VT, J Med Chem, 2025, Maciag M and Karamyan VT, Nat Rev Drug Discov, 2025). This comprehensive panel combines both critical and emerging safety targets, providing broader in vitro secondary pharmacology profiling.
No. of Assays on Panel:
127
Assays on Panel:
Family
Neurotransmitter Metabolism
Name
Acetylcholinesterase Human Enzymatic LeadHunter Assay - TW
Item
104010
Protein
Acetylcholinesterase
Organism
Human
Assay Sub Type
Enzymatic
Family
Protease
Name
ACE Human Angiotensin-Converting Metallo Peptidase Enzymatic LeadHunter Assay - TW
Item
107310
Protein
ACE
Organism
Human
Assay Sub Type
Enzymatic
Family
Transporter
Name
ATPase (Na+/K+) Human HeLa S3 Cell Enzymatic LeadHunter Assay – TW
Item
107720
Protein
Na+/K+ ATPase
Organism
Human
Assay Sub Type
Enzymatic
Family
Epigenetic
Name
BRD4 (BD1) Human Bromodomain-Containing 4 Binding LeadHunter Assay - TW
Item
107800
Protein
BRD4 (BD1)
Organism
Human
Assay Sub Type
Binding
Family
Cytosolic (Other)
Name
Carbonic Anhydrase 2 Human Enzymatic LeadHunter Assay - TW
Item
112020
Protein
Carbonic Anhydrase 2
Organism
Human
Assay Sub Type
Enzymatic
Family
Protease
Name
Cathepsin D Human Pepsin Aspartic Peptidase Enzymatic LeadHunter Assay - TW
Item
112350
Protein
Cathepsin D
Organism
Human
Assay Sub Type
Enzymatic
Family
Protease
Name
Cathepsin G Human Chymotrypsin Serine Peptidase Enzymatic LeadHunter Assay - TW
Item
112510
Protein
Cathepsin G
Organism
Human
Assay Sub Type
Enzymatic
Family
Protease
Name
MMP1 Human Matrix Metallopeptidase Enzymatic LeadHunter Assay - TW
Item
114110
Protein
MMP1
Organism
Human
Assay Sub Type
Enzymatic
Family
Protease
Name
MMP9 Human Matrix Metallopeptidase Enzymatic LeadHunter Assay - TW
Item
114910
Protein
MMP9
Organism
Human
Assay Sub Type
Enzymatic
Family
Lipid Metabolism
Name
COX1 Human Cyclooxygenase Enzymatic LeadHunter Assay - TW
Item
116030
Protein
COX1
Organism
Human
Assay Sub Type
Enzymatic
Family
Lipid Metabolism
Name
COX2 Human Cyclooxygenase Enzymatic LeadHunter Assay - TW
Item
118030
Protein
COX2
Organism
Human
Assay Sub Type
Enzymatic
Family
Oxidoreductase
Name
HMG-CoA Reductase Human Enzymatic LeadHunter Assay - TW
Item
124020
Protein
HMG-CoA Reductase
Organism
Human
Assay Sub Type
Enzymatic
Family
Oxidoreductase
Name
Monoamine Oxidase A (MAO-A) Human Enzymatic LeadHunter Assay - TW
Item
140010
Protein
MAO-A
Organism
Human
Assay Sub Type
Enzymatic
Family
Oxidoreductase
Name
Monoamine Oxidase B (MAO-B) Human Enzymatic LeadHunter Assay - TW
Item
140120
Protein
MAO-B
Organism
Human
Assay Sub Type
Enzymatic
Family
PDE
Name
PDE3A Human Phosphodiesterase Enzymatic LeadHunter Assay - TW
Item
152300
Protein
PDE3A
Organism
Human
Assay Sub Type
Enzymatic
Family
PDE
Name
PDE4D2 Human Phosphodiesterase Enzymatic LeadHunter Assay - TW
Item
154420
Protein
PDE4D
Organism
Human
Assay Sub Type
Enzymatic
Family
PDE
Name
PDE5A Human Phosphodiesterase Enzymatic LeadHunter Assay - TW
Item
156020
Protein
PDE5A
Organism
Human
Assay Sub Type
Enzymatic
Family
PDE
Name
PDE10A2 Human Phosphodiesterase Enzymatic LeadHunter Assay - TW
Item
156500
Protein
PDE10A
Organism
Human
Assay Sub Type
Enzymatic
Family
Protease
Name
ECE1 Human Neprilysin Metallo Peptidase Enzymatic LeadHunter Assay - TW
Item
163950
Protein
ECE1
Organism
Human
Assay Sub Type
Enzymatic
Family
Protease
Name
Neutral Endopeptidase Human Neprilysin Metallo Peptidase Enzymatic LeadHunter Assay - TW
Item
164010
Protein
Neutral Endopeptidase
Organism
Human
Assay Sub Type
Enzymatic
Family
Protease
Name
MALT1 Human Paracaspase Cysteine Peptidase Enzymatic LeadHunter Assay - TW
Item
164020
Protein
MALT1
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
PI3Kgamma (PIK3CG) (p120gamma) Human PtdIns(4,5)P 3-Kinase Enzymatic ADP-Glo [10 uM ATP] Kinase LeadHunter Assay - TW
Item
167030
Protein
PI3Kgamma
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
PDHK1 Human PDHK Kinase Enzymatic ADP-Glo [10 μM ATP] Kinase LeadHunter Assay - TW
Item
167041
Protein
PDHK1
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
ATM Human PIKK Kinase Enzymatic HTRF [100 μM ATP] Kinase LeadHunter Assay - TW
Item
167070
Protein
ATM
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
Aurora-A Human Other Protein Kinase Enzymatic Radiometric Assay [10 μM ATP] - TW
Item
167100
Protein
Aurora-A
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
Aurora-B Human Other Protein Kinase Enzymatic Radiometric LeadHunter Assay [10 μM ATP] - TW
Item
167130
Protein
Aurora-B
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
EGFR Human RTK Kinase Enzymatic Radiometric LeadHunter Assay [10 μM ATP] - TW
Item
170020
Protein
EGFR
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
ROCK1 Human AGC Kinase Enzymatic Radiometric LeadHunter Assay [10 μM ATP] - TW
Item
171520
Protein
ROCK1
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
ROCK2 Human AGC Kinase Enzymatic Radiometric LeadHunter Assay [10 μM ATP] - TW
Item
171550
Protein
ROCK2
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
CLIK (STK35) Human Other Protein Kinase Enzymatic Radiometric [10 µM ATP] Kinase LeadHunter Assay - TW
Item
171585
Protein
STK35
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
FGFR Human RTK Kinase Enzymatic Radiometric LeadHunter Assay [10 μM ATP] - TW
Item
171790
Protein
FGFR1
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
Flt-1 (VEGFR1) Human RTK Kinase Enzymatic Radiometric LeadHunter Assay [10 μM ATP] - TW
Item
171800
Protein
Flt-1 (VEGFR1)
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
KDR (VEGFR2) Human RTK Kinase Enzymatic Radiometric Assay [10 μM ATP] - TW
Item
171820
Protein
KDR (VEGFR2)
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
FAK Human TK Kinase Enzymatic Radiometric Assay [10 μM ATP] - TW
Item
173000
Protein
FAK
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
Kit Human RTK Kinase Enzymatic Radiometric Assay [10 μM ATP] - TW
Item
174100
Protein
Kit
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
IR Human RTK Kinase Enzymatic Radiometric LeadHunter Assay [10 μM ATP] - TW
Item
174990
Protein
IR
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
TRKA Human RTK Kinase Enzymatic Radiometric LeadHunter Assay [10 μM ATP] - TW
Item
175040
Protein
TRKA
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
Lck Human TK Kinase Enzymatic Radiometric LeadHunter Assay [10 μM ATP] - TW
Item
176020
Protein
Lck
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
MAP2K7 (MKK7) Human STE Kinase Enzymatic Radiometric [10 µM ATP] LeadHunter Assay - TW
Item
176115
Protein
MAPKK7
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
GSK3beta Human CMGC Kinase Enzymatic Radiometric LeadHunter Assay [10 μM ATP] - TW
Item
176500
Protein
GSK3beta
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
Src Human TK Kinase Enzymatic Radiometric LeadHunter Assay [10 μM ATP] - TW
Item
176810
Protein
Src
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
PKCalpha Human PKC Kinase Enzymatic Radiometric LeadHunter Assay [10 μM ATP] - TW
Item
180010
Protein
PKCa
Organism
Human
Assay Sub Type
Enzymatic
Family
CYP450
Name
Thromboxane Synthase (CYP5A1) Human CYP450 Enzymatic LeadHunter Assay - TW
Item
194020
Protein
Thromboxane Synthase
Organism
Human
Assay Sub Type
Enzymatic
Family
Oxidoreductase
Name
Xanthine Oxidase Bovine Enzymatic LeadHunter Assay - TW
Item
198000
Protein
Xanthine Oxidase
Organism
Bovine
Assay Sub Type
Enzymatic
Family
Lipid Metabolism
Name
5-LO Human Lipoxygenase Enzymatic LeadHunter Assay - TW
Item
199021
Protein
5-LO
Organism
Human
Assay Sub Type
Enzymatic
Family
GPCR
Name
A1 Human Adenosine GPCR Binding Antagonist Radioligand LeadHunter Assay - TW
Item
200510
Protein
A1
Organism
Human
Assay Sub Type
Binding
Family
GPCR
Name
A2A Human Adenosine GPCR Binding Agonist Radioligand LeadHunter Assay - TW
Item
200610
Protein
A2A
Organism
Human
Assay Sub Type
Binding
Family
Transporter
Name
Adenosine Human Transporter Binding Antagonist Radioligand LeadHunter Assay - TW
Item
202020
Protein
Organism
Human
Assay Sub Type
Binding
Family
GPCR
Name
alpha1A Human Adrenoceptor GPCR Binding Antagonist Radioligand LeadHunter Assay - TW
Item
203110
Protein
alpha1A
Organism
Human
Assay Sub Type
Binding
Family
GPCR
Name
alpha1B Human Adrenoceptor GPCR Binding Antagonist Radioligand LeadHunter Assay - TW
Item
203210
Protein
alpha1B
Organism
Human
Assay Sub Type
Binding
Family
GPCR
Name
alpha1D Human Adrenoceptor GPCR Binding Antagonist Radioligand LeadHunter Assay - TW
Item
203400
Protein
alpha1D
Organism
Human
Assay Sub Type
Binding
Family
GPCR
Name
alpha2A Human Adrenoceptor GPCR Binding Antagonist Radioligand LeadHunter Assay - TW
Item
203630
Protein
alpha2A
Organism
Human
Assay Sub Type
Binding
Family
GPCR
Name
alpha2B Human Adrenoceptor GPCR Binding Antagonist Radioligand LeadHunter Assay - TW
Item
203710
Protein
alpha2B
Organism
Human
Assay Sub Type
Binding
Family
GPCR
Name
beta1 Human Adrenoceptor GPCR Binding Antagonist Radioligand LeadHunter Assay - TW
Item
204010
Protein
beta1
Organism
Human
Assay Sub Type
Binding
Family
GPCR
Name
beta2 Human Adrenoceptor GPCR Binding Antagonist Radioligand LeadHunter Assay - TW
Item
204110
Protein
beta2
Organism
Human
Assay Sub Type
Binding
Family
Transporter
Name
NET Human Norepinephrine Transporter Binding Antagonist Radioligand LeadHunter Assay - TW
Item
204410
Protein
NET
Organism
Human
Assay Sub Type
Binding
Family
NHR
Name
AR Human Androgen NHR Binding Agonist Radioligand LeadHunter Assay - TW
Item
206000
Protein
AR
Organism
Human
Assay Sub Type
Binding
Family
GPCR
Name
AT1 Human Angiotensin GPCR Binding Antagonist Radioligand LeadHunter Assay - TW
Item
210030
Protein
AT1
Organism
Human
Assay Sub Type
Binding
Family
GPCR
Name
B2 Human Bradykinin GPCR Binding Agonist Radioligand LeadHunter Assay - TW
Item
212620
Protein
B2
Organism
Human
Assay Sub Type
Binding
Family
Ion Channel
Name
Cav1.2 (L-type) Rat Calcium Ion Channel Binding (Diltiazem Site) LeadHunter Assay - TW
Item
214510
Protein
Cav1.2 (L-type)
Organism
Rat
Assay Sub Type
Binding
Family
Ion Channel
Name
Cav1.2 (L-type) Human Calcium Ion Channel Binding (Dihydropyridine Site) LeadHunter Assay - TW
Item
214610
Protein
Cav1.2 (L-type)
Organism
Human
Assay Sub Type
Binding
Family
Ion Channel
Name
Cav1.2 (L-type) Rat Calcium Ion Channel Binding (Verapamil Site) LeadHunter Assay - TW
Item
215000
Protein
Cav1.2 (L-type)
Organism
Rat
Assay Sub Type
Binding
Family
Ion Channel
Name
Cav2.2 (N-type) Rat Calcium Ion Channel Binding Antagonist Radioligand LeadHunter Assay - TW
Item
216000
Protein
Cav2.2 (N-type)
Organism
Rat
Assay Sub Type
Binding
Family
GPCR
Name
CB1 Human Cannabinoid GPCR Binding Antagonist Radioligand LeadHunter Assay - TW
Item
217050
Protein
CB1
Organism
Human
Assay Sub Type
Binding
Family
GPCR
Name
CB2 Human Cannabinoid GPCR Binding Agonist Radioligand LeadHunter Assay - TW
Item
217100
Protein
CB2
Organism
Human
Assay Sub Type
Binding
Family
GPCR
Name
CCR1 Human Chemokine GPCR Binding Agonist Radioligand LeadHunter Assay - TW
Item
217510
Protein
CCR1
Organism
Human
Assay Sub Type
Binding
Family
GPCR
Name
CCK1 (CCKA) Human Cholecystokinin GPCR Binding Agonist Radioligand LeadHunter Assay - TW
Item
218030
Protein
CCK1 (CCKA)
Organism
Human
Assay Sub Type
Binding
Family
GPCR
Name
CCK2 (CCKB) Human Cholecystokinin GPCR Binding Agonist Radioligand LeadHunter Assay - TW
Item
218130
Protein
CCK2 (CCKB)
Organism
Human
Assay Sub Type
Binding
Family
GPCR
Name
D1 Human Dopamine GPCR Binding Antagonist Radioligand LeadHunter Assay - TW
Item
219500
Protein
D1
Organism
Human
Assay Sub Type
Binding
Family
GPCR
Name
D2L Human Dopamine GPCR Binding Antagonist Radioligand LeadHunter Assay - TW
Item
219600
Protein
D2
Organism
Human
Assay Sub Type
Binding
Family
GPCR
Name
D2S Human Dopamine GPCR Binding Antagonist Radioligand LeadHunter Assay - TW
Item
219700
Protein
D2
Organism
Human
Assay Sub Type
Binding
Family
GPCR
Name
D3 Human Dopamine GPCR Binding Antagonist Radioligand LeadHunter Assay - TW
Item
219800
Protein
D3
Organism
Human
Assay Sub Type
Binding
Family
Transporter
Name
DAT Human Dopamine Transporter Binding Antagonist Radioligand LeadHunter Assay - TW
Item
220320
Protein
DAT
Organism
Human
Assay Sub Type
Binding
Family
GPCR
Name
ETA Human Endothelin GPCR Binding Agonist Radioligand LeadHunter Assay - TW
Item
224010
Protein
ETA
Organism
Human
Assay Sub Type
Binding
Family
NHR
Name
ERalpha Human Estrogen NHR Binding Agonist Radioligand LeadHunter Assay - TW
Item
226010
Protein
ERalpha
Organism
Human
Assay Sub Type
Binding
Family
Transporter
Name
GABA (Non-Selective) Rat Transporter Binding Antagonist Radioligand LeadHunter Assay - TW
Item
226400
Protein
Organism
Rat
Assay Sub Type
Binding
Family
Ion Channel
Name
GABAA (Non-Selective) Rat Ion Channel [3H] Flunitrazepam Binding Agonist Radioligand LeadHunter Assay - TW
Item
226600
Protein
Organism
Rat
Assay Sub Type
Binding
Family
Ion Channel
Name
GABAA (Non-Selective) Rat Ion Channel [3H] Ro-15-1788 Binding (Hippocampus) LeadHunter Assay - TW
Item
226630
Protein
Organism
Rat
Assay Sub Type
Binding
Family
Ion Channel
Name
GABAA (Non-Selective) Rat Ion Channel [3H] TBOB Binding Antagonist Radioligand LeadHunter Assay - TW
Item
226810
Protein
Organism
Rat
Assay Sub Type
Binding
Family
GPCR
Name
GABAB (B1a/B2) Human GABAB GPCR Binding Antagonist Radioligand LeadHunter Assay - TW
Item
228610
Protein
GABAB (B1/B2)
Organism
Human
Assay Sub Type
Binding
Family
NHR
Name
GR Human Glucocorticoid NHR Binding Agonist Radioligand LeadHunter Assay - TW
Item
232030
Protein
GR
Organism
Human
Assay Sub Type
Binding
Family
Ion Channel
Name
Glutamate (AMPA, Non-Selective) Rat Ion Channel [3H] AMPA Binding LeadHunter Assay - TW
Item
232600
Protein
Organism
Rat
Assay Sub Type
Binding
Family
Ion Channel
Name
Glutamate (Kainate, Non-Selective) Rat Ion Channel [3H] Kainic acid Binding LeadHunter Assay - TW
Item
232710
Protein
Organism
Rat
Assay Sub Type
Binding
Family
Ion Channel
Name
Glutamate (NMDA, NR1/NR2A) Human Ion Channel [3H] CGP-39653 Binding LeadHunter Assay - TW
Item
232820
Protein
GluN1/ GluN2A
Organism
Human
Assay Sub Type
Binding
Family
Ion Channel
Name
Glutamate (NMDA, Non-Selective) Rat Ion Channel [3H] MDL 105,519 Binding LeadHunter Assay - TW
Item
232910
Protein
Organism
Rat
Assay Sub Type
Binding
Family
Ion Channel
Name
Glutamate (Non-Selective) Rat Ion Channel [3H] TCP Binding LeadHunter Assay - TW
Item
233000
Protein
Organism
Rat
Assay Sub Type
Binding
Family
Ion Channel
Name
Glutamate (NMDA, Non-Selective) Rat Ion Channel [3H] Ifenprodil Binding LeadHunter Assay - TW
Item
234000
Protein
Organism
Rat
Assay Sub Type
Binding
Family
GPCR
Name
mGlu5 Human Glutamate (Metabotropic) GPCR Binding Agonist Radioligand LeadHunter Assay - TW
Item
237000
Protein
mGlu5
Organism
Human
Assay Sub Type
Binding
Family
Ion Channel
Name
Glycine alpha1 Human Ion Channel [3H] Strychnine Binding LeadHunter Assay - TW
Item
239010
Protein
GLRA1
Organism
Human
Assay Sub Type
Binding
Family
GPCR
Name
H1 Human Histamine GPCR Binding Antagonist Radioligand LeadHunter Assay - TW
Item
239610
Protein
H1
Organism
Human
Assay Sub Type
Binding
Family
GPCR
Name
H2 Human Histamine GPCR Binding Antagonist Radioligand LeadHunter Assay - TW
Item
239710
Protein
H2
Organism
Human
Assay Sub Type
Binding
Family
GPCR
Name
CXCR2 (IL-8RB) Human Chemokine GPCR Binding Agonist Radioligand LeadHunter Assay - TW
Item
244500
Protein
CXCR2 (IL-8RB)
Organism
Human
Assay Sub Type
Binding
Family
GPCR
Name
CysLT1 Human Leukotriene GPCR Binding Agonist Radioligand LeadHunter Assay - TW
Item
250460
Protein
CysLT1
Organism
Human
Assay Sub Type
Binding
Family
GPCR
Name
MC1 Human Melanocortin GPCR Binding Agonist Radioligand LeadHunter Assay - TW
Item
251100
Protein
MC1
Organism
Human
Assay Sub Type
Binding
Family
GPCR
Name
MC4 Human Melanocortin GPCR Binding Agonist Radioligand LeadHunter Assay - TW
Item
251350
Protein
MC4
Organism
Human
Assay Sub Type
Binding
Family
GPCR
Name
M1 Human Acetylcholine (Muscarinic) GPCR Binding Antagonist Radioligand LeadHunter Assay - TW
Item
252610
Protein
M1
Organism
Human
Assay Sub Type
Binding
Family
GPCR
Name
M2 Human Acetylcholine (Muscarinic) GPCR Binding Antagonist Radioligand LeadHunter Assay - TW
Item
252710
Protein
M2
Organism
Human
Assay Sub Type
Binding
Family
GPCR
Name
M3 Human Acetylcholine (Muscarinic) GPCR Binding Antagonist Radioligand LeadHunter Assay - TW
Item
252810
Protein
M3
Organism
Human
Assay Sub Type
Binding
Family
GPCR
Name
M4 Human Acetylcholine (Muscarinic) GPCR Binding Antagonist Radioligand LeadHunter Assay - TW
Item
252910
Protein
M4
Organism
Human
Assay Sub Type
Binding
Family
GPCR
Name
NK1 Human Tachykinin GPCR Binding Agonist Radioligand LeadHunter Assay - TW
Item
255520
Protein
NK1
Organism
Human
Assay Sub Type
Binding
Family
GPCR
Name
NK3 Human Tachykinin GPCR Binding (Agonist Radioligand) Assay, Panlabs
Item
255710
Protein
NK3
Organism
Human
Assay Sub Type
Binding
Family
GPCR
Name
Y1 Human Neuropeptide Y GPCR Binding Agonist Radioligand LeadHunter Assay - TW
Item
257010
Protein
NPY1R
Organism
Human
Assay Sub Type
Binding
Family
Ion Channel
Name
nAChR (alpha1) Human Ion Channel Binding Antagonist Radioligand LeadHunter Assay - TW
Item
258700
Protein
nAChR-a1
Organism
Human
Assay Sub Type
Binding
Family
Ion Channel
Name
nAChR (alpha3/beta4) Human Ion Channel Binding Agonist Radioligand LeadHunter Assay - TW
Item
258730
Protein
nAChR-a3b4
Organism
Human
Assay Sub Type
Binding
Family
GPCR
Name
delta (DOP) Human Opioid GPCR Binding Antagonist Radioligand LeadHunter Assay - TW
Item
260130
Protein
delta (DOP)
Organism
Human
Assay Sub Type
Binding
Family
GPCR
Name
kappa (KOP) Human Opioid GPCR Binding Antagonist Radioligand LeadHunter Assay - TW
Item
260210
Protein
kappa (KOP)
Organism
Human
Assay Sub Type
Binding
Family
GPCR
Name
mu (MOP) Human Opioid GPCR Binding Antagonist Radioligand LeadHunter Assay - TW
Item
260410
Protein
mu (MOP)
Organism
Human
Assay Sub Type
Binding
Family
Ion Channel
Name
KATP Hamster Potassium Ion Channel Binding Antagonist Radioligand LeadHunter Assay - TW
Item
265600
Protein
KATP
Organism
Hamster
Assay Sub Type
Binding
Family
Ion Channel
Name
Kv1.1 Human Potassium Channel Binding Antagonist Radioligand LeadHunter Assay – TW
Item
265710
Protein
Kv1.1
Organism
Human
Assay Sub Type
Binding
Family
Ion Channel
Name
hERG Human Potassium Ion Channel [3H] Dofetilide Binding Antagonist Radioligand LeadHunter Assay - TW
Item
265910
Protein
hERG
Organism
Human
Assay Sub Type
Binding
Family
NHR
Name
PPARgamma Human NHR Binding Agonist Radioligand LeadHunter Assay - TW
Item
267500
Protein
PPARgamma
Organism
Human
Assay Sub Type
Binding
Family
NHR
Name
RARalpha Human Retinoic Acid NHR Binding (Agonist Radioligand) Assay, Panlabs
Item
269200
Protein
RARalpha
Organism
Human
Assay Sub Type
Binding
Family
GPCR
Name
5-HT1A Human Serotonin GPCR Binding Agonist Radioligand LeadHunter Assay - TW
Item
271110
Protein
5-HT1A
Organism
Human
Assay Sub Type
Binding
Family
GPCR
Name
5-HT1B Human Serotonin GPCR Binding Antagonist Radioligand LeadHunter Assay - TW
Item
271230
Protein
5-HT1B
Organism
Human
Assay Sub Type
Binding
Family
GPCR
Name
5-HT2A Human Serotonin GPCR Binding Antagonist Radioligand LeadHunter Assay - TW
Item
271650
Protein
5-HT2A
Organism
Human
Assay Sub Type
Binding
Family
GPCR
Name
5-HT2B Human Serotonin GPCR [3H] LSD Binding Agonist Radioligand LeadHunter Assay - TW
Item
271700
Protein
5-HT2B
Organism
Human
Assay Sub Type
Binding
Family
GPCR
Name
5-HT2C Human Serotonin GPCR Binding Antagonist Radioligand LeadHunter Assay - TW
Item
271800
Protein
5-HT2C
Organism
Human
Assay Sub Type
Binding
Family
Ion Channel
Name
5-HT3 Human Serotonin Ion Channel Binding Antagonist Radioligand LeadHunter Assay - TW
Item
271910
Protein
5-HT3A
Organism
Human
Assay Sub Type
Binding
Family
GPCR
Name
5-HT6 Human Serotonin GPCR Binding Agonist Radioligand LeadHunter Assay - TW
Item
272200
Protein
5-HT6
Organism
Human
Assay Sub Type
Binding
Family
Transporter
Name
SERT Human Serotonin Transporter Binding Antagonist Radioligand LeadHunter Assay - TW
Item
274030
Protein
SERT
Organism
Human
Assay Sub Type
Binding
Family
Ion Channel
Name
Nav1.5 Sodium Channel Human Ion Channel [3H]BNZA Binding LeadHunter Assay - TW
Item
279520
Protein
Nav1.5
Organism
Human
Assay Sub Type
Binding
Family
GPCR
Name
V1A Human Vasopressin / Oxytocin GPCR Binding Antagonist Radioligand LeadHunter Assay - TW
Item
287530
Protein
V1A
Organism
Human
Assay Sub Type
Binding
Family
NHR
Name
PR Human Progesterone NHR Binding Agonist Radioligand LeadHunter Assay - TW
Item
299005
Protein
PR
Organism
Human
Assay Sub Type
Binding
Family
Ion Channel
Name
nAChR (alpha4/beta2) Human Ion Channel Binding Agonist Radioligand LeadHunter Assay - TW
Item
299031
Protein
nAChR-a4b2
Organism
Human
Assay Sub Type
Binding
Family
GPCR
Name
PAF Human Platelet-Activating Factor GPCR Binding Agonist Radioligand LeadHunter Assay - TW
Item
299037
Protein
PAF
Organism
Human
Assay Sub Type
Binding
Family
GPCR
Name
GPBA (TGR5) Human Bile Acid GPCR Cell Based Agonist cAMP LeadHunter Assay - TW
Item
304110-0
Protein
GPBAR
Organism
Human
Assay Sub Type
Cell Based
Family
GPCR
Name
MRGX2 (MRGPRX2) Human Class A Orphan GPCR Cell Based Agonist IP1 LeadHunter Assay - TW
Item
331840-0
Protein
Mas-related G-protein coupled receptor member X2
Organism
Human
Assay Sub Type
Cell Based
Assay Information
Platform:
Plate reader
Testing Information
Test Concentration / Dose:
Suggested concentration for initial testing is 10 µM
Test Sample Requirements:
270 μL of a 10 mM stock or 1.5 mg pre-weighed powder (assuming FW≦500 and purity 100%)
Turnaround Time
Standard:
10 Business Days
Clinical Relevance
Adverse / Beneficial Action:
Potential adverse effects across multiple organ systems
Additional Information
Brand:
SafetyScreen
Testing Location:
Taiwan - Taipei
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