Biological Information
Family:
Epigenetic
Sub Family:
Histone Methyltransferase (HMT)
Class:
Writer
Protein Name:
ASH1L
Uniprot Number:
Q9NR48
Gene Name:
ASH1L
Gene ID:
55870
Gene Aliases:
huASH1|ASH1|ASH1L1|KMT2H
Accession Number:
NM_018489
Organism:
Human
Construct Details:
Recombinant
Assay Information
Assay Type:
Biochemical
Assay Sub Type:
Enzymatic
Functional Mode:
Antagonist
Detection Method:
Radiometric
Measured Response:
Scintillation
Testing Information
Substrate:
Polynucléosome (1.5 µg/ml)
Tracer:
[3H] SAM (150nM)
Incubation:
15 min at RT
Control Inhibitor:
SAH
Test Concentration / Dose:
Eurofins will provide IC/EC50 calculation if 5 or more concentrations are selected.
Test Sample Requirements:
Minimum for 1) Screen: 60 μl of 10 mM stock -OR- 1 mg (pre-weighed) for 10µM final testing. 2) Dose Response: 90 μl of 10 mM stock -OR- 1 mg (pre-weighed) for a top concentration at 10 µM.
Minimum Order Quantity:
10
Turnaround Time
Standard:
15 Business Days
Reference Compound Data
Additional Information
Brand:
LeadHunter
Testing Location:
France - Celle L'Evescault