MC1 Mouse Melanocortin GPCR Binding Agonist Radioligand LeadHunter Assay - FR

Background Information:

Melanocortins belong to the superfamily of seven transmembrane G-protein-coupled receptors, which constitute one of the major signal transduction systems in eukaryotic cells. Coding sequences for these receptors, in those regions believed to contribute to the agonist-antagonist binding site, are strongly conserved across mammalian species. The melanocortin MC1 receptor is made primarily in melanocytes, MC2 in adrenal cortex, MC3 and MC4 almost exclusively neuronal, and MC5 in exocrine gland cells.

Family:

GPCR

Sub Family:

Melanocortin

Class:

Class A

Protein Name:

MC1

Uniprot Number:

Q01726 (human)

Protein Aliases:

alpha melanocyte stimulating hormone receptor

Gene Name:

MC1R

Gene ID:

4157

Gene Aliases:

MSH-R|MSHR

Accession Number:

NM_002386

Organism:

Mouse