beta1 Human Adrenoceptor GPCR Cell Based Antagonist cAMP LeadHunter Assay - FR

Background Information:

Adrenoreceptors belong to the superfamily of G protein-coupled seven transmembrane proteins. G-protein-coupled receptors constitute one of the major signal transduction systems in eukaryotic cells. Coding sequences for these receptors, in those regions believed to contribute to the agonist-antagonist binding site, are strongly conserved across mammalian species. Adrenoreceptors are found in most peripheral tissue and within the central nervous system.

Family:

GPCR

Sub Family:

Adrenoceptor

Class:

Class A

Protein Name:

beta1

Uniprot Number:

P08588

Protein Aliases:

Beta-1 adrenoceptor

Gene Name:

ADRB1

Gene ID:

153

Accession Number:

NM_000684

Organism:

Human

Construct Details:

Recombinant

Cell Type:

HEK293