Biological Information
Family:
Ion Channel
Sub Family:
Transient Potential
Class:
Voltage-Gated
Protein Name:
TRPV1
Uniprot Number:
Q8NER1
Gene Name:
TRPV1
Gene ID:
7442
Accession Number:
NM_018727
Organism:
Human
Construct Details:
Recombinant
Cell Type:
CHO-S
Assay Information
Assay Type:
Functional
Assay Sub Type:
Cell Based
Functional Mode:
Antagonist
Detection Method:
Fluorimetry
Measured Response:
Fluorescence
Testing Information
Incubation:
RT
Control Inhibitor:
capsazepine
Control Activator:
capsaicin (30 nM)
Test Concentration / Dose:
Eurofins will provide IC/EC50 calculation if 5 or more concentrations are selected.
Test Sample Requirements:
Minimum for 1) Screen: 225 μl of 10 mM stock -OR- 1 mg (pre-weighed) for 10µM final testing. 2) Dose Response: 280 μl of 10 mM stock -OR- 1 mg (pre-weighed) for a top concentration at 10 µM.
Minimum Order Quantity:
16
Turnaround Time
Standard:
15 Business Days
Reference Compound Data
Clinical Relevance
Therapeutic Area:
CNS/Addiction/Pain
Additional Information
Brand:
LeadHunter
Testing Location:
France - Celle L'Evescault
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