Protein Binding Services

The binding of therapeutic compounds to plasma or serum proteins is an important factor to consider when assessing the Absorption, Distribution, Metabolism, Excretion (ADME) and Pharmacokinetics (PK) profile of a drug. The degree of protein binding can have a significant impact on the free unbound drug concentration, thereby limiting the amount of drug distributed into tissues in the body which can have dramatic effects on both drug metabolism and efficacy.
 
Eurofins Discovery offers a panel of protein binding services enabling you to better understand the plasma protein binding characteristics of your compounds. With state-of-the-art equipment and scientific expertise in DMPK, we are focused on providing cost-effective, high-quality, reproducible data and flexible solutions with fast turnaround times.
 
When combined with our comprehensive panel of bioavailability assays, including drug absorption, solubility, and permeability services, Eurofins Discovery protein binding assays can be used to help you prioritize compounds for further development. Our protein binding assays are available for testing in standard human and animal plasma, and can be ordered individually, combined or as a selection of key services provided in our drug candidate assessment packages to provide cost savings.