Acetylcholinesterase Human Enzymatic LeadHunter Assay - FR

Background Information:

Acetylcholinesterase (ACES, AchE, EC 3.1.1.7)) terminates the action of acetylcholine (ACh) at the junctions of various cholinergic nerve endings with their effector organs or postsynaptic sites. Compounds that inhibit AChE are called anticholinesterase agents and are used to ameliorate the symptoms of myesthenia gravis, lower intraocular pressure in glaucoma and for possible treatment of dementia through increase of ACh concentration in the brain. Anticholinesterases may also cause salivation, meiosis, increase in gastrointestinal motility, skeletal muscle paralysis, respiratory arrest and cardiovascular collapse. These agents are also used as insecticides and pesticides for agricultural purposes and vector control.

Family:

Enzyme

Sub Family:

Acetylcholine turnover

Protein Name:

AChE

Uniprot Number:

P22303

Protein Aliases:

Yt blood group

Gene Name:

ACHE

Gene ID:

43

Accession Number:

NM_015831

Organism:

Human

Construct Details:

Recombinant