OVERVIEW
DOCUMENTS/REFERENCES
Biological Information
Background Information:
The BioMAP Oncology Early Screening Service (StroHT29) is a high quantity screening format in BioMAP oncology system StroHT29, comprised of dermal fibroblasts, the HT-29 colorectal adenocarcinoma cell line, and peripheral blood mononuclear cells. This stromal TME model is stimulated via the T cell receptor for 48-hrs to recapitulate the activation of tumor infiltrating immune cells in the context of an immunosuppressive cancer cell line and normal host stromal tissue. Biomarker readouts capture impacts on translationally relevant immune, matrix remodeling, and inflammation related intratumoral responses. This service allows for rapid testing of 18 compounds at 4 concentrations for immuno-oncology potential in human tumor microenvironment models.
Organism:
Human
Assay Information
Assay Type:
Functional
Assay Sub Type:
Cell Based
Testing Information
Test Sample Requirements:
For Small Molecules, 50 ul of 1000X stock solution in 100% DMSO per agent. For Biologics, 500 ul of 100X stock solution in PBS or water per agent.
Minimum Order Quantity:
72
Turnaround Time
Standard:
30 Business Days
Clinical Relevance
Therapeutic Area:
Oncology/Immuno-Oncology
Additional Information
Brand:
BioMAP
Testing Location:
USA - St Charles, MO
RELATED SOLUTIONS
BioMAP Systems ELECT Menu 3 (StroHT29)
Item: 89-0003-0045
BioMAP Combo ELECT Menu 3 (StroHT29)
Item: 89-0015-0045
BioMAP Oncology Panel (CRC)
Item: 89-0044-0901
BioMAP Oncology Early Screening Service (VascHT29)
Item: 89-0047-0046
OncoPanel® Proliferation Assay in HT-29 Cells, 3-day Multi-Parameter High Content Imaging
Item: HT2MP03
OncoPanel® Proliferation Assay in HT-29 Cells, 5-day Multi-Parameter High Content Imaging
Item: HT2MP05
OncoPanel® Proliferation Assay in HT-29 Cells, 10-day Multi-Parameter High Content Imaging
Item: HT2MP10
OncoPanel® Proliferation Assay in HT-29 Cells, 3-day Singleplex High Content Imaging
Item: HT2SP03
OncoPanel® Proliferation Assay in HT-29 Cells, 5-day Singleplex High Content Imaging
Item: HT2SP05
OncoPanel® Proliferation Assay in HT-29 Cells, 10-day Singleplex High Content Imaging
Item: HT2SP10
OncoPanel® 3D Spheroid Viability Assay in HT-29 Cells
Item: HT2SP3D
OncoPanel®, Full 3D Spheroid Panel, with 2D Control, Cell Viability
Item: PSOP0001
OncoPanel®, Full 3D Spheroid Panel, without 2D Control, Cell Viability
Item: PSOP0002
OncoPanel®, Full Panel: Custom Assay
Item: PSOP0003
OncoPanel®, Full Panel: High Content Imaging Cell Proliferation Assay, 10-day long-term
Item: PSOP0010
OncoPanel®, Full Panel: High Content Imaging Cell Proliferation Assay, 3-day
Item: PSOP0011
OncoPanel®, Full Panel: High Content Imaging Cell Proliferation Assay, 5-day
Item: PSOP0012
OncoPanel®, Full Panel: Multi-Parameter High Content Profiling Assay, 10-day long-term
Item: PSOP0013
OncoPanel®, Full Panel: Multi-Parameter High Content Profiling Assay, 3-day
Item: PSOP0014
OncoPanel®, Full Panel: Multi-Parameter High Content Profiling Assay, 5-day
Item: PSOP0015
Questions? Contact Us
You can easily get in touch with a Eurofins Discovery Expert or get help from our Customer Service team. Reach out with questions, or to discuss your specific discovery challenges.
