OVERVIEW
DOCUMENTS/REFERENCES
Biological Information
Background Information:
The BioMAP Oncology Early Screening Service (VascHT29) is a high quantity screening format in BioMAP oncology system VascHT29, comprised of peripheral blood mononuclear cells, the HT-29 colorectal adenocarcinoma cell line, and venular endothelial cells. This vascular TME model is stimulated via the T cell receptor for 48 hrs to recapitulate the activation of tumor infiltrating immune cells in the context of an immunosuppressive cancer cell line and normal host vascular tissue. Biomarker readouts capture impacts on translationally relevant immune, angiogenesis, and inflammation related intertumoral responses. This service allows for rapid testing of 18 compounds at 4 concentrations for immuno-oncology potential in human tumor microenvironment models.
Organism:
Human
Assay Information
Assay Type:
Functional
Assay Sub Type:
Cell Based
Testing Information
Test Sample Requirements:
For Small Molecules, 50 ul of 1000X stock solution in 100% DMSO per agent. For Biologics, 500 ul of 100X stock solution in PBS or water per agent.
Minimum Order Quantity:
72
Turnaround Time
Standard:
30 Business Days
Clinical Relevance
Therapeutic Area:
Oncology/Immuno-Oncology
Additional Information
Brand:
BioMAP
Testing Location:
USA - St Charles, MO
RELATED SOLUTIONS
BioMAP Systems ELECT Menu 3 (VascHT29)
Item: 89-0003-0046
BioMAP Combo ELECT Menu 3 (VascHT29)
Item: 89-0015-0046
BioMAP Oncology Panel (CRC)
Item: 89-0044-0901
BioMAP Oncology Early Screening Service (StroHT29)
Item: 89-0047-0045
OncoPanel® Proliferation Assay in HT-29 Cells, 3-day Multi-Parameter High Content Imaging
Item: HT2MP03
OncoPanel® Proliferation Assay in HT-29 Cells, 5-day Multi-Parameter High Content Imaging
Item: HT2MP05
OncoPanel® Proliferation Assay in HT-29 Cells, 10-day Multi-Parameter High Content Imaging
Item: HT2MP10
OncoPanel® Proliferation Assay in HT-29 Cells, 3-day Singleplex High Content Imaging
Item: HT2SP03
OncoPanel® Proliferation Assay in HT-29 Cells, 5-day Singleplex High Content Imaging
Item: HT2SP05
OncoPanel® Proliferation Assay in HT-29 Cells, 10-day Singleplex High Content Imaging
Item: HT2SP10
OncoPanel® 3D Spheroid Viability Assay in HT-29 Cells
Item: HT2SP3D
OncoPanel®, Full 3D Spheroid Panel, with 2D Control, Cell Viability
Item: PSOP0001
OncoPanel®, Full 3D Spheroid Panel, without 2D Control, Cell Viability
Item: PSOP0002
OncoPanel®, Full Panel: Custom Assay
Item: PSOP0003
OncoPanel®, Full Panel: High Content Imaging Cell Proliferation Assay, 10-day long-term
Item: PSOP0010
OncoPanel®, Full Panel: High Content Imaging Cell Proliferation Assay, 3-day
Item: PSOP0011
OncoPanel®, Full Panel: High Content Imaging Cell Proliferation Assay, 5-day
Item: PSOP0012
OncoPanel®, Full Panel: Multi-Parameter High Content Profiling Assay, 10-day long-term
Item: PSOP0013
OncoPanel®, Full Panel: Multi-Parameter High Content Profiling Assay, 3-day
Item: PSOP0014
OncoPanel®, Full Panel: Multi-Parameter High Content Profiling Assay, 5-day
Item: PSOP0015
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