Biological Information
Background Information:
Panel of two BioMAP systems incorporating colorectal adenocarcinoma cells and stimulated to recapitulate and model tumor-immune-stromal or tumor-immune-vascular microenvironments and relevant signaling pathways that manifest during tumorigenesis. The StroHT29 system is comprised of dermal fibroblasts, the HT-29 colorectal adenocarcinoma cell line, and peripheral blood mononuclear cells to model to stromal tumor microenvironment. The VascHT29 system is comprised of venular endothelial cells, the HT-29 colorectal adenocarcinoma cell line, and peripheral blood mononuclear cells to model the vascular tumor microenvironment.
No. of Assays on Panel:
2
Assays on Panel:
Family
Name
BioMAP Systems ELECT Menu 3 (StroHT29)
Item
89-0003-0045
Protein
Organism
Human
Assay Sub Type
Cell Based
Family
Name
BioMAP Systems ELECT Menu 3 (VascHT29)
Item
89-0003-0046
Protein
Organism
Human
Assay Sub Type
Cell Based
Organism:
Human
Assay Information
Assay Type:
Functional
Assay Sub Type:
Cell Based
Testing Information
Test Concentration / Dose:
Four concentrations per test agent in triplicate
Test Sample Requirements:
For Small Molecules: 120uL of a 1000X stock based on the top concentration being tested & standard 3-fold dilutions. For Biologics: 1.2mL of a 100X stock in PBS or water, based on the top concentration being tested & standard 3-fold dilutions
Turnaround Time
Standard:
40 Business Days
Clinical Relevance
Therapeutic Area:
Oncology/Immuno-Oncology
Additional Information
Brand:
BioMAP
Testing Location:
USA - St Charles, MO
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