Biological Information

Background Information:

The BioMAP Fibrosis Early Screening Service (REMyoF) is a high quantity screening format in the BioMAP fibrosis system REMyoF, comprised of renal proximal tubule epithelial cells and lung fibroblasts. This system is stimulated with profibrotic and proinflammatory factors to model the biology of renal fibrosis and inflammation associated with chronic kidney diseases and end-stage renal failure. Biomarker readouts capture impacts on translationally relevant matrix remodeling, tissue repair, wound healing, and inflammation related responses in the diseased kidney. This service allows for rapid testing of 18 compounds at 4 concentrations for antifibrotic development potential in a human fibrosis model.

Organism:

Human

Assay Information

Assay Type:

Functional

Assay Sub Type:

Cell Based

Testing Information

Test Sample Requirements:

For Small Molecules, 50 ul of 1000X stock solution in 100% DMSO per agent. For Biologics, 500 ul of 100X stock solution in PBS or water per agent.

Minimum Order Quantity:

72

Turnaround Time

Standard:

30 Business Days

Clinical Relevance

Therapeutic Area:

Fibrosis

Additional Information

Brand:

BioMAP

Testing Location:

USA - St Charles, MO

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