OVERVIEW
DOCUMENTS/REFERENCES
Biological Information
Background Information:
The BioMAP Fibrosis Early Screening Service (SAEMyoF) is a high quantity screening format in the BioMAP fibrosis system SAEMyoF, comprised of small airway epithelial cells and lung fibroblasts. This system is stimulated with profibrotic and proinflammatory factors to model the biology of fibrotic lung diseases such as idiopathic pulmonary fibrosis. Biomarker readouts capture impacts on translationally relevant matrix remodeling, tissue repair, and inflammation related responses in the diseased lung. This service allows for rapid testing of 18 compounds at 4 concentrations for antifibrotic development potential in a human fibrosis model.
Organism:
Human
Assay Information
Assay Type:
Functional
Assay Sub Type:
Cell Based
Testing Information
Test Sample Requirements:
For Small Molecules, 50 ul of 1000X stock solution in 100% DMSO per agent. For Biologics, 500 ul of 100X stock solution in PBS or water per agent.
Minimum Order Quantity:
72
Turnaround Time
Standard:
30 Business Days
Clinical Relevance
Therapeutic Area:
Fibrosis
Additional Information
Brand:
BioMAP
Testing Location:
USA - St Charles, MO
RELATED SOLUTIONS
BioMAP Systems ELECT Menu 2 (SAEMyoF)
Item: 89-0003-0042
BioMAP Combo ELECT Menu 2 (SAEMyoF)
Item: 89-0015-0042
BioMAP Fibrosis Panel
Item: 89-0016-0904
BioMAP Fibrosis Early Screening Service (MyoF)
Item: 89-0049-0011
BioMAP Fibrosis Early Screening Service (REMyoF)
Item: 89-0049-0040
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