Tools for Hit-to-Lead Success

Tools for Hit-to-Lead Success

Developing a hit-to-lead is one of the longest and most challenging stages of drug discovery. At Eurofins Discovery, we have drawn on our 40+ years of experience to continuously innovate our industry-leading portfolio to rapidly progress customer programs and help you navigate this complex journey.
 
Extend the capacity and expertise of your team with our scientists to confirm the structure-activity relationship (SAR) of your target of interest through a series of customizable in vitro primary and safety pharmacology, as well as ADME profiling services. With Eurofins Discovery guiding you step by step along the journey, get to the clinic faster with a highly validated and optimized lead candidate.

Key Areas

Your organization may have a novel target, pathway, or phenotype of interest, or a new approach in a well-explored area—along with challenges in program implementation.

Our chemistry services drive preclinical success by combining synthetic, computational, medicinal, and analytical chemistry with biology, delivering optimized molecules through an integrated, data-driven approach. With labs located strategically in Spain, US & India, we provide flexible Chemistry services to accelerate your Drug Discovery program.

Leverage our state-of-the-art facilities utilizing robotics, data processing and control to screen for activity in our highly validated and scalable target-based assays.

Our computational chemistry expertise enhances drug discovery by leveraging molecular modeling, structure-based design, and AI-driven insights to optimize hit identification, lead development, and candidate selection.

Explore our comprehensive antibody discovery services using in vitro and in vivo platforms to generate high-quality therapeutic antibodies.

Discover comprehensive protein production services, leveraging bacterial, insect, and mammalian expression systems for high-quality, scalable protein.

Gain an early understanding of your lead compounds’ drug-like properties of absorption, distribution, metabolism, and excretion (ADME), as well as potential toxicities, from our growing portfolio of over 600 assays.

Develop Safer Preclinical Candidates with Industry-leading, Reliable and Robust In Vitro Safety Assays and Panels

Phenotypic drug discovery gives you a head start on clinical success with translationally relevant biomarkers as functional readouts for insights on mechanism of action, efficacy, and toxicity assessments.